Category: Clinical

Download E-books Cardiac Glycosides: Part II: Pharmacokinetics and Clinical Pharmacology PDF

By Liv Storstein (auth.), Professor Dr. med. Kurt Greeff (eds.)

The pharmacokinetics of digitalis glycosides were the topic of in depth re­ view (IISALO, 1977; ARONSON, 1980; PERRIER et ai., 1977). learn on glycoside kinetics has advanced at a quick speed, requiring carrying on with reevaluation of the kingdom of our realizing of this challenge. the current article makes a speciality of the impression of affliction states (renal, gastrointestinal, thyroid, and cardiac) at the absorption, distribution, and clearance of a couple of digitalis glycosides. facts is seriously reviewed, and interpreted with recognize to attainable scientific implications. A. Renal Insufficiency I. Strophanthin Strophanthin disposition in renal failure has been evaluated in just stories. KRAMER et ai. (1970) decided an removal half-life of 14 h in normals as com­ pared to 60 h in anuric sufferers. related effects have been said via BRASS and Pm­ LIPPS (1970) utilizing tritiated strophanthin. they discovered a half-life worth of 18 h in fit members compared to sixty eight h in anuric sufferers. The findings in actual fact in­ dicate that the removing half-life of strophanthin is lengthy in renal failure.

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Download E-books Clinical Aspects of Cardiac Arrhythmias PDF

By S. M. Cobbe (auth.), A. John Camm, David E. Ward (eds.)

We have been rather happy to assemble this quantity entitled 'Clinical features of Cardiac Arrhythmias'. fresh years have visible the book of many textbooks on cardiac arrhythmias, a few of which be aware of one specific point similar to drug administration, electrocardiographic appearances, electrophysiological review and so forth; and others of that are the collated experiences of symposia, frequently facing exact con­ siderations of hugely specialized difficulties. many of the higher extra accomplished texts have dedicated a considerable share to uncomplicated issues and experimental observations, some distance faraway from the medical area. while requested to give a contribution to the sequence 'Current prestige of scientific Cardiology' we felt that the medical features of cardiac arrhyth­ mias may be emphasised, and that the textual content may be as entire as attainable in the barriers of a unmarried quantity during this sequence. This accomplished yet scientific process has necessitated the inclusion of convinced topics akin to the mechanisms of tachycardia, metabolic elements of cardiac arrhythmias and reperfusion arrhythmias, which aren't at once or solely medical. besides the fact that, the fast advances in those parts in recent times are inclined to have more and more very important medical con seq uences. even supposing the epidemiology of scientific arrhythmias is hard to dis­ disguise, it really is largely favored that arrhythmias are commonplace.

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Download E-books Gynecological Cancers: Genetic and Epigenetic Targets and Drug Development (Current Clinical Oncology) PDF

By Antonio Giordano, Marcella Macaluso

Facilitating the collaboration among the fundamental, translational, and scientific sciences, this publication presents an summary of the genetic and epigenetic mechanisms underlying the formation and development of gynecological cancers. Gynecological Cancers: Genetic and Epigenetic goals and Drug Development gathers all the molecular and mobile facets of gynecological melanoma jointly inside one quantity, delivering specific and up to date details at the etiology, prognosis, and remedy of gynecological cancers. 

Gynecological Cancers: Genetic and Epigenetic goals and Drug Development ​also discusses the racial and ethnic disparities within the remedy of gynecological cancers via within your means modalities like unmarried stopover at screening and analysis, good girls clinics, and cellular clinics. Written and edited through leaders within the box, this quantity inside of the Current medical Oncology sequence is an vital source for today’s training oncologist.

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Download E-books Infectious Disease in the Aging: A Clinical Handbook PDF

By Thomas T. Yoshikawa (auth.), Dean Norman, Thomas Yoshikawa (eds.)

Because getting older is followed through a gentle decline in resistance to infectious illnesses, the prognosis and therapy of those illnesses within the aged isn't just even more advanced, but in addition frequently really assorted from that for more youthful sufferers. In Infectious affliction within the getting older: A scientific guide, second Edition, a panel of famous and hugely skilled geriatric physicians and infectious affliction specialists evaluate crucial universal infections affecting the aged and delineate their well-proven diagnostic, healing, and preventative concepts. one of the health problems discusses are urinary tract infections, pneumonia, ocular infections, tuberculosis, and fungal and viral infections. There are distinct dialogue of sepsis, infective endocarditis, intraabdominal infections, bacterial meningitis, osteomyelitis and septic arthritis, and prosthetic equipment infections. furthermore, this 2d variation contains new chapters on Herpes zoster, HIV/AIDS, and SARS and West Nile Virus.
Comprehensive, informative, and simply available, Infectious ailment within the getting older: A medical instruction manual, second Edition, deals all physicians treating geriatric sufferers the fastest and newest consultant to figuring out, prognosis, therapy, and prevention of infectious ailment difficulties within the aged today.

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Download E-books Clinical Evaluation of Medical Devices: Principles and Case Studies PDF

By Karen Becker Witkin (auth.), Karen Becker Witkin (eds.)

In scientific overview of clinical units Karen Becker Witkin and her special colleagues summarize for the 1st time the most important rules and techniques for use in clinical gadget medical trials, after which exhibit the implementation of those rules in a revealing sequence of specific, real-world case reports. construction at the options utilized in scientific trials of prescription drugs, those hugely skilled participants convey tips on how to layout and evaluation scientific trials of scientific units, in addition to how top to assemble facts that's applicable to the FDA. in addition they clarify while, why, and the way scientific learn matches into the improvement and advertising of recent product recommendations and spell out foreign regulatory standards for examine and registration of scientific units. 9 designated case reviews illustrate the big variety of research designs which were effectively utilized to many various study difficulties and numerous healing or diagnostic items.

medical review of scientific units won't simply play a key position in constructing medical trials of scientific units as a rigorous technology, but in addition supply modern basically resource of case-study-based functional info on how scientific research layout ideas are top adapted to the winning overview of novel scientific units.

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Download E-books Clinical Pharmacology: Current Topics and Case Studies PDF

By Markus Müller (auth.), Univ.-Prof. Dr. Markus Müller (eds.)

this day we witness an eventful time within which the robust new forces of genomics, details know-how and economics are swiftly altering the technological know-how and paintings of medication. this may require extra specialization than ever prior to. notwithstanding, there's additionally an expanding call for for an built-in technique, that's supplied through the self-discipline of medical Pharmacology (CP). CP pursues a systematic aim by means of learning drug motion in sufferers and volunteers, a scientific objective by way of administering applicable drug remedy and a regulatory target through assessing the risk/benefit ratio of drug applicants in drug improvement and compensation. This creation to present themes of CP covers conventional subject matters of scientific drug learn and trial technique but additionally offers perception in present themes like genomics, imaging know-how and matters in drug compensation. a couple of concrete case stories in medical drug study and improvement aid to offer a greater realizing of the overall ideas of CP.

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Download E-books Clinical Aspects of Dysphasia PDF

By Martin L. Albert M. D., Harold Goodglass Ph. D., Nancy A. Helm D. Sc., Alan B. Rubens M. D., Michael P. Alexander M. D. (auth.)

This quantity is one in a sequence of monographs being issued lower than the overall name of "Disorders of Human Communication". every one monograph offers intimately with a specific point of vocal verbal exchange and its problems, and is written by means of across the world individual specialists. consequently, the sequence will supply an authoritative resource of updated clinical and scientific informa­ tion when it comes to the total box of ordinary and irregular speech conversation, and as such will prevail the sooner huge paintings "Handbuch der Stimm­ und Sprachheilkunde" by way of R. Luchsinger and G. E. Arnold (last issued in 1970). This sequence will turn out helpful for clinicians, lecturers and examine staff in phoniatrics and logopaedics, phonetics and linguistics, speech pathology, otolaryngology, neurology and neurosurgery, psychology and psychiatry, paediatrics and audiology. numerous of the monographs can be important to voice and making a song academics, and to their scholars. G. E. Arnold, Jackson, leave out. F. Winckel, Berlin B. D. Wyke, London Preface Neurologists, neuropsychologists, speech pathologists and different clinicians who take care of dysphasic sufferers have frequently complained that on hand books on dysphasia are usually parochially theoretical, and insufficiently directed in the direction of medical fact. those books give you the different types, labels, and theoretical speculations of 1 college or one other; yet dysphasic sufferers as frequently as now not don't healthy smartly right into a particular theoretical class. medical styles of dysphasic syndromes of such a lot sufferers with dysphasia hardly ever conform absolutely to the images painted within the textbooks.

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Download E-books Malformations of the Nervous System, Volume 87: Handbook of Clinical Neurology (Series Editors: Aminoff, Boller and Swaab) by Elsevier (2007-11-19) PDF

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Brigham and Women's medical institution, Boston, MA. offers clinicians and citizens with a present evaluate of a few of the advances within the pathophysiology, prognosis, and administration of sufferers with acute coronary syndromes. good points new checks, brokers, ways, and regimens. past variation: c1999. DNLM: Coronary Disease--therapy.

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